i've seen ScriptRegion with python support.

- is it possible to create smath plugins/extensions in python?
- is there any simple IronPython plugin available for help?

Wrote

is it possible to create smath plugins/extensions in python?

Theoretically, yes, you can. But assemblies that are not purely managed are not supported by the program (skips them when loading). If the assembly has a dependency on kernel32.dll or similar, then it will be skipped by the plugin manager.

Wrote

is there any simple IronPython plugin available for help?

No.